Selective Detection of Penicillin G Antibiotic in Milk by Molecularly Imprinted Polymer-Based Plasmonic SPR Sensor
Monireh Bakhshpour, Ilgım Göktürk, Nilay Bereli̇, Fatma Yılmaz, A. Deni̇zli̇
- Yazarlar
- Monireh Bakhshpour, Ilgım Göktürk, Nilay Bereli̇, Fatma Yılmaz, A. Deni̇zli̇
- Yayın
- Biomimetics 2021
- DOI
- 10.3390/biomimetics6040072
- Atıflar
- 27
Özet
Molecularly imprinted polymer-based surface plasmon resonance sensor prepared using silver nanoparticles was designed for the selective recognition of Penicillin G (PEN-G) antibiotic from both aqueous solution and milk sample. PEN-G imprinted sensors (NpMIPs) SPR sensor was fabricated using poly (2-hydroxyethyl methacrylate-N-methacroyl-(L)-cysteine methyl ester)-silver nanoparticles-N-methacryloyl-L-phenylalanine methyl ester polymer by embedding silver nanoparticles (AgNPs) into the polymeric film structure. In addition, a non-imprinted (NpNIPs) SPR sensor was prepared by utilizing the same polymerization recipe without addition of the PEN-G template molecule to evaluate the imprinting effect. FTIR-ATR spectrophotometer, ellipsometer, contact angle measurements were used for the characterization of NpMIPs SPR sensors. The linear concentration range of 0.01–10 ng/mL PEN-G was studied for kinetic analyses. The augmenting effect of AgNPs used to increase the surface plasmon resonance signal response was examined using polymer-based PEN-G imprinted (MIPs) sensor without the addition of AgNPs. The antibiotic amount present in milk chosen as a real sample was measured by spiking PEN-G into the milk. According to the Scatchard, Langmuir, Freundlich and Langmuir–Freundlich adsorption models, the interaction mechanism was estimated to be compatible with the Langmuir model.
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Monireh Bakhshpour, Ilgım Göktürk, Nilay Bereli̇, Fatma Yılmaz, A. Deni̇zli̇ (2021). Selective Detection of Penicillin G Antibiotic in Milk by Molecularly Imprinted Polymer-Based Plasmonic SPR Sensor. Biomimetics. https://doi.org/10.3390/biomimetics6040072
BibTeX
@article{monireh2021,
title = {Selective Detection of Penicillin G Antibiotic in Milk by Molecularly Imprinted Polymer-Based Plasmonic SPR Sensor},
author = {Monireh Bakhshpour and Ilgım Göktürk and Nilay Bereli̇ and Fatma Yılmaz and A. Deni̇zli̇},
journal = {Biomimetics},
doi = {10.3390/biomimetics6040072},
year = {2021}
}