Biosensors
Electrochemical Biosensors · Optical Biosensors
Development of novel biosensor platforms for rapid and sensitive detection of biomarkers, pathogens, and environmental contaminants.
Learn moreResearch
Cutting-edge research in biosensors and biodiagnostics
Virus Detection
Molecular Imprinting · Aptamer-based Detection
Advanced molecular diagnostics for rapid and accurate detection of viral pathogens including Ebola, HIV, Zika, and SARS-CoV.
Learn moreBiochromatography
Affinity Chromatography · Ion Exchange
Chromatographic separation techniques for purification and analysis of biological molecules and pharmaceuticals.
Learn moreNanomaterials
Magnetic Nanoparticles · Quantum Dots
Synthesis and characterization of nanomaterials for biosensing applications and targeted drug delivery systems.
Learn moreHemoperfusion
Toxin Removal · Protein Adsorption
Development of biocompatible sorbents for blood purification and therapeutic applications.
Learn moreCancer Diagnostics
Tumor Markers · Circulating DNA
Early detection methods for cancer biomarkers using innovative biosensor technologies.
Learn moreCurrent projects
Ongoing research initiatives
- Advanced Chromatographic Materials (TÜBİTAK)
Development of novel monolithic and particulate materials for high-performance bioseparations.
- Point-of-Care Testing Device Development (Industry)
Collaborative project with industry partner to develop commercial point-of-care diagnostic devices for infectious diseases.
- Molecularly Imprinted Biosensors for Cancer Biomarkers (TÜBİTAK)
Novel molecularly imprinted polymer-based sensors for early detection of circulating tumor markers in blood samples.
- Rapid Diagnostic Platform for Emerging Pathogens (EU Horizon)
Development of a portable, multiplexed biosensor platform for rapid detection of emerging viral pathogens in resource-limited settings.
Research since 1996
The topics the group worked on in its first decades, and the current areas that carry them on.
Biochemistry
Hemoperfusion and removal of toxic materials (bilirubin, pathogenic antibodies, cholesterol, metal ions such as iron and cadmium) from blood; artificial kidney systems; interactions of enzymes and proteins with polymeric surfaces; polymer-based biospecific sorbents; purification of enzymes and proteins by bioaffinity, hydrophobic, dye and membrane affinity, and immobilised metal chelate affinity chromatography.
Biomaterials
Production of polymeric biomaterials, characterisation of surface and bulk structures, and modification by chemical and biological methods.
Controlled drug release
Controlled release of anticancer drugs from polymeric matrices, mathematical models of controlled release, and transdermal release systems.
Environmental technology
Toxicity limits in industrial waste water, removal of heavy metals with polymeric adsorbents and its mathematical modelling, and waste management.
Food technology
Large-scale purification of rennin from sheep stomach by isoelectric precipitation.
Membrane technology
Porous membranes, enzyme immobilisation, and membranes for removing heavy metals from natural waters.
Polymer technologies
Polymers with tailored surface and bulk properties, shapes and geometries, and their use in medicine and biology.
Sensor technologies
SPR and QCM sensors and their applications in environmental, clinical, forensic and food analysis.
Tissue engineering
Plasma polymerisation and immobilisation of liver cells (hepatocytes) on chemically and biologically modified polymer surfaces.
More from the group
Selected Publications
Denizli, A., Pişkin, E., Dye-Ligand Affinity Systems, Journal of Biochemical and Biophysical Methods, 49(1-3) 391-416, 2001. Bere…
OpenTopics
Biochemistry Hemoperfusion-Removal of Toxic Materials (bilirubin, pathogenic antibodies, cholesterol, metal ions such as iron and…
OpenPopular Articles
14 items
Open50th Year Books
15 items
Fifteen books published for Hacettepe University's 50th year, free to read online.
OpenBooks of Erhan Pişkin
11 items
The founding generation: books by Prof. Dr. Erhan Pişkin, mentor of the group.
OpenJournal & Book Covers
50 items
OpenInterviews
10 items
Open