Cancer Diagnostics

Overview

Early detection methods for cancer biomarkers using innovative biosensor technologies.

Early detection is crucial for successful cancer treatment. Our research focuses on developing highly sensitive and specific biosensors for detecting cancer biomarkers at early stages when treatment is most effective.

Research Areas

Tumor Markers

Detection of protein biomarkers associated with various cancers.

  • PSA (Prostate cancer)
  • CEA (Colorectal cancer)
  • CA-125 (Ovarian cancer)
  • AFP (Liver cancer)
  • HER2 (Breast cancer)
  • Cardiac troponins

Circulating DNA

Detection of cell-free tumor DNA (ctDNA) in blood samples.

  • Mutation detection
  • Methylation analysis
  • Copy number variations
  • Microsatellite instability

Exosome Detection

Analysis of tumor-derived extracellular vesicles for cancer diagnosis.

  • Exosome isolation methods
  • Surface marker analysis
  • Exosomal miRNA profiling
  • Protein cargo analysis

Liquid Biopsy

Non-invasive sampling methods for cancer monitoring.

  • Circulating tumor cells (CTCs)
  • Cell-free DNA analysis
  • Exosome analysis
  • Tumor-educated platelets

Current project

Molecularly Imprinted Biosensors for Cancer Biomarkers

TÜBİTAK · 2023-2026 · ₺5M

Novel molecularly imprinted polymer-based sensors for early detection of circulating tumor markers in blood samples.

Key publications