Virus Detection

Overview

Advanced molecular diagnostics for rapid and accurate detection of viral pathogens including Ebola, HIV, Zika, and SARS-CoV.

Our virus detection research addresses critical global health challenges by developing rapid, sensitive, and cost-effective diagnostic tools. We focus on creating platforms that can be deployed in both clinical laboratories and resource-limited settings.

Research Areas

Molecular Imprinting

We develop molecularly imprinted polymers (MIPs) that act as synthetic antibodies for specific virus recognition. These materials offer advantages of stability, reusability, and low cost compared to biological antibodies.

• Whole virus imprinting
• Epitope imprinting
• Surface imprinting techniques
• Computational design of MIPs

Aptamer-based Detection

Aptamers are single-stranded DNA or RNA molecules that can bind to specific targets with high affinity. We develop aptamer-based sensors for various viral pathogens.

• SELEX selection of virus-specific aptamers
• Aptamer-functionalized nanoparticles
• Electrochemical aptasensors
• Lateral flow aptamer assays

Nanoparticle Platforms

Nanomaterials enhance sensor performance through signal amplification and improved surface area for biorecognition.

• Gold nanoparticle-based colorimetric detection
• Magnetic nanoparticle concentration
• Carbon nanotube sensors
• Quantum dot labeling

Target Pathogens

• SARS-CoV-2
• Ebola virus
• HIV
• Zika virus
• Hepatitis viruses
• Influenza
• Dengue
• Norovirus

Current project

Key publications